# Pet Biotech Companies Advance Lifespan, Cloning, and Cryopreservation Services

> US-based companies are developing drugs to extend dog lifespans, offering pet cloning, and providing cryopreservation, reflecting a growing market for pet-related biotechnologies.

By PrimaryBrief newsroom · Published 2026-10-22T04:05:30.483746Z
Canonical: https://primarybrief.com/article/pet-biotech-companies-advance-lifespan-cloning-and-cryopreservation-services-2bf49278

In October 2026, pet biotechnology companies, primarily based in the United States, are offering a range of services from longevity-enhancing drugs to pet cloning and cryopreservation, with costs for cloning reaching $50,000 to $100,000 [1][8][9]. This sector addresses a deep human desire to prolong companionship with animals and manage grief [1].

This emerging field of pet biotechnology is pushing scientific and regulatory boundaries. Pet owners now have options to extend their pets' lives, replicate them genetically, or preserve them for a theoretical future revival, raising ethical discussions about animal welfare and the understanding of life and death [1].

## What the records show

Loyal, a San Francisco-based animal health biotech company, is developing drugs to extend the healthy lifespan of dogs [3]. One such drug, LOY-002, is a daily pill designed for senior dogs aged 10 years or older and weighing at least 14 pounds [1][7]. The drug targets metabolic changes linked to aging, aiming to improve insulin sensitivity and lower insulin levels [7]. As of January 2026, US regulators accepted Loyal's safety data for LOY-002 [1]. The company has also completed the preliminary-effectiveness and target-animal-safety sections for the drug [2]. Loyal expects to apply for conditional approval for LOY-002 in 2027 [1]. The company's large-scale STAY study enrolled approximately 1,300 senior dogs across 70 veterinary clinics nationwide, with the goal of giving dogs “one healthier year” [2][4].

Rejuvenate Bio, co-founded by CEO Daniel Oliver and CTO Noah Davidsohn, is developing gene therapies to treat age-related diseases in dogs, with the aim of extending their healthspan [6]. The company licensed its technology from the Wyss Institute and Harvard Medical School [6]. Rejuvenate Bio has secured funding, including from the Department of Defense's Small Business Innovation Research program, and has partnered with companies like Merck Animal Health [5][6]. They are conducting a pilot study focused on mitral valve disease in Cavalier King Charles Spaniels, a condition that affects millions of dogs [6].

Pet cloning services are available from companies such as Texas-based ViaGen Pets & Equine, which charges $50,000 to clone a dog or cat [1][8]. Spain's Ovoclone offers similar services, with costs ranging from $50,000 to $100,000 [9]. Ovoclone reports a low success rate of 2% to 3% for surviving clones, often requiring multiple attempts [9]. ViaGen Pets began cloning pet dogs and cats in 2015 [10].

Cryopreservation services are also offered for pets, with companies like Cryopets in Salt Lake City, Utah, preserving deceased pets at very low temperatures [11][12]. Experts, however, caution that revival is highly unlikely with current scientific capabilities [1]. PerPETuate, Inc. has been preserving DNA from animals since 1998, with stored cells used for cloning and medical purposes [14].

## The timeline

*   **1998**: PerPETuate, Inc. founded as the world's first pet genetic preservation company [14].
*   **2015**: ViaGen Pets & Equine begins cloning pet dogs and cats [10].
*   **February 2020**: Rejuvenate Bio licenses gene therapy technology from the Wyss Institute and Harvard Medical School [6].
*   **January 2026**: US regulators accept Loyal's safety data for its drug LOY-002 [1].
*   **June 2026**: Merck Animal Health partners with Rejuvenate Bio to develop therapies targeting age-related diseases in pets [5].
*   **2027 (Expected)**: Loyal expects to apply for conditional approval for LOY-002 [1].

## What changed and for whom

Pet owners now have more scientific options to address the aging and loss of their companion animals, though these come with significant costs and varying probabilities of success [1][8][9]. The development of drugs like Loyal's LOY-002, which aims to extend healthy lifespans, offers a new approach to managing age-related health decline in dogs [7]. For those facing the loss of a pet, cloning and cryopreservation provide avenues for genetic replication or long-term preservation, even if the outcome of revival is uncertain [1][9]. This growth in pet biotech has opened new markets for animal health companies and created new regulatory challenges for agencies like the FDA [1][2][4].

## What the subject has said publicly

Celine Halioua, founder of Loyal, stated the company's mission is to extend dogs' healthy lives, with an unofficial slogan of “save the dogs, save the world” [4]. Daniel Oliver, CEO and co-founder of Rejuvenate Bio, expressed excitement about translating gene therapy work from mice to dogs, citing a “dearth of treatment options to combat age-related diseases” in canines [6]. Noah Davidsohn, CTO and co-founder of Rejuvenate Bio, stated the company's passion for dog health, aiming to “get rid of the morbidities associated with aging” [6]. Kerry Ryan, Animal Care Director for ViaGen Pets & Equine, explained that pet owners interested in cloning often want “a piece of their pets around forever,” recognizing the strong human-animal bond [10].

## What we could not confirm

We could not confirm the specific timeline for Rejuvenate Bio's gene therapies beyond their current pilot study [6]. The ultimate success rates for lifespan extension drugs in dogs, beyond preliminary effectiveness findings, were not confirmed [2][7]. We also could not confirm if any cryopreserved pets have ever been successfully revived [1].

## Evidence cited
1. Can’t bear to say goodbye to your pet? Biotech’s got you covered. (thenextweb.com) — https://thenextweb.com/news/cant-bear-to-say-goodbye-to-your-pet-biotechs-got-you-covered
2. Loyal is clearly ahead in pet longevity drugs, and the gap is wide. It is the only startup with a broad canine longevity medicine close enough to FDA conditional approval for a near-term veterinary launch to look realistic. The lead is regulatory before it is financial. Loyal has completed the preliminary-effectiveness and target-animal-safety sections for LOY-002, leaving manufacturing as the last major technical requirement disclosed for possible conditional approval. Loyal has also built an o (newmarketpitch.com) — https://newmarketpitch.com/loyal-longevity-drugs-fda-conditional-approval/
3. Loyal (loyal.com) — https://www.loyal.com/
4. Forbes: Can We Delay Aging in Dogs? The Biotech Company Leading a Quiet Revolution (youtube.com) — https://www.youtube.com/watch?v=s0e5aLzC8eM
5. Merck Animal Health partners Rejuvenate Bio in canine longevity push (longevity.technology) — https://www.longevity.technology/merck-animal-health-partners-rejuvenate-bio-gene-therapy/
6. Rejuvenate Bio licenses Wyss Institute gene therapy technology for aging-related diseases in dogs - Wyss Institute at Harvard University (harvard.edu) — https://wyss.harvard.edu/news/rejuvenate-bio-licenses-wyss-institute-gene-therapy-technology-for-aging-related-diseases-in-dogs/
7. Loyal moves closer to FDA approval for dog longevity pill (consumeraffairs.com) — https://www.consumeraffairs.com/news/loyal-moves-closer-to-fda-approval-for-dog-longevity-pill-102126.html
8. Dog Cloning (viagenpets.com) — https://www.viagenpets.com/dog-cloning
9. Pet cloning: A big business with a growing ethical dilemma - Los Angeles Times (latimes.com) — https://www.latimes.com/world-nation/story/2025-11-18/pet-cloning-a-big-business-with-a-growing-ethical-dilemma
10. Exploring the science and ethics behind pet cloning (dvm360.com) — https://www.dvm360.com/view/exploring-the-science-and-ethics-behind-pet-cloning
11. Cryopets - Preserve your pet's memory for the future (cryopets.com) — https://www.cryopets.com/
12. Cryopets - BioPedia (miraheze.org) — https://miraheze.org/wiki/Cryopets
13. This Peter Thiel-backed startup wants to freeze your pets' bodies for all eternity (businessinsider.com) — https://www.businessinsider.com/pet-cryonics-startup-cryopets-peter-thiel-2023-12
14. PerPETuate, Inc. - Pet Genetic Preservation (perpetuate.net) — https://perpetuate.net/
15. Pet Suspensions – Cryonics Institute (cryonics.org) — https://www.cryonics.org/pet-suspensions
16. Pet cryopreservation by Tomorrow.bio — Europe's longest-running cryopreservation organisation. (tomorrow.bio) — https://tomorrow.bio/pet-cryopreservation
17. tomorrow.bio (tomorrow.bio) — https://tomorrow.bio/